MRI findings of autoimmune hepatitis and brief review of the literature
Abstract
Autoimmune hepatitis is a form of chronic hepatitis of unknown etiology. Imaging is not included in the diagnostic criteria of the disease, but it may play a role in histopathologic correlation and monitoring of these patients. Certain nonspecific imaging patterns of autoimmune hepatitis may be associated with inflammation or fibrosis. Our purpose is to review the magnetic resonance imaging findings of autoimmune hepatitis, any possible correlation with histopathology and their role in assessing the follow up of these patients.
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Gossard AA, Lindor KD. Autoimmune hepatitis: a review. J Gastroenterol 2012; 47:498-503.
Krawitt EL. Autoimmune hepatitis. N Engl J Med 2006; 354:54-66.
Manns MP, Czaja AJ, Gorham JD, et al. Diagnosis and management of autoimmune hepatitis. Hepatology 2010; 51(6):2193-2213.
Lewin M, Vilgrain V, Ozenne V, et al. Prevalence of sclerosing cholangitis in adults with autoimmune hepatitis: a prospective magnetic resonance imaging and histological study. Hepatology 2009; 50:528-537.
Malik N, Venkatesh SK. Imaging of autoimmune hepatitis and overlap syndromes. Abdom Radiol 2017; 42:19-27.
Liberal R, Grant CR, Longhi MS, et al. Diagnostic criteria of autoimmune hepatitis. Autoimmunity Reviews 2014; 13:435-440.
Czaja AJ, Freese DK. Diagnosis and treatment of autoimmune hepatitis. Hepatology 2002; 36(2):479-497.
Knowlton JQ, Taylor AJ, Reichelderfer M, Stang J. Imaging of biliary tract inflammation: an update. AJR 2008; 190:984-992.
Liberal R, Grant CR. Cirrhosis and autoimmune liver disease: Current understanding. World J Hepatol 2016; 8(28):1157-1168.
Werner M, Prytz H, Ohlsson B, et al. Epidemiology and the initial presentation of autoimmune hepatitis in Sweden: a nationwide study. Scand J Gastroenterol 2008; 43: 1232-1240
Verma S, Gunuwan B, Mendler M, et al. Factors predicting relapse and poor outcome in type I autoimmune hepatitis: role of cirrhosis development, patterns of transaminases during remission and plasma cell activity in the liver biopsy. Am J Gastroenterol 2004; 99: 1510-1516
Feld JJ, Dinh H, Arenovich T, et al. Autoimmune hepatitis: effect of symptoms and cirrhosis on natural history and outcome. Hepatology 2005; 42: 53-62
Sahni VA, Raghunathan G, Mearadji B, et al. Autoimmune hepatitis: CT and MR imaging features with histopathological correlation. Abdom Imaging 2010; 35:75-84.
Semelka RC, Chung J-J, Hussain SM, et al. Chronic hepatitis: Correlation of early patchy and late linear enhancement patterns on gadolinium-enhanced MR images with histopathology initial experience. J Magn Reson Imaging 2001; 13:385-391.
Bilaj F, Hyslop WB, Rivero H, et al. MR imaging findings in Autoimmune Hepatitis: Correlation with clinical staging. Radiology 2005; 236:896-902.
Marti-Bonmati L, Delgado F. MR imaging in liver cirrhosis: classical and new approaches. Insights Imaging 2010; 1:233-244.
Onishi H, Theisen D, Zachoval R, et al. Intrahepatic diffuse periportal enhancement patterns on hepatobiliary phase gadoxetate disodium-enhanced liver MR images. Do they correspond to periportal hyperintense patterns on T2-weighted images? Medicine 2019; 98:11(e14784).
Ly NJ, Miller FH. Periportal contrast enhancement and abnormal signal intensity on state-of-the-art MR images. AJR 2001; 176:891-897.
Hyslop WB, Kierans AS, Leonardou P, et al. Overlap syndrome of autoimmune chronic liver diseases: MR findings. J Magn Reson Imaging 2010; 31:383-389.
Dodd GD, Baron RL, Oliver JH, Federle MP. End-stage primary sclerosing cholangitis: CT findings of hepatic morphology in 36 patients. Radiology 1999; 211:357-362.
Qayyum A, Graser A, Westphalen A, et al. CT of benign hypervascular liver nodules in autoimmune hepatitis. AJR 2004; 183:1573-1576.
Park SZ, Nagorney DM, Czaja AJ. Hepatocellular carcinoma in autoimmune hepatitis. Dig Dis Sci 2000; 45:1944-1948.
Teufel A, Weinmann A, Centner C, et al. Hepatocellular carcinoma in patients with autoimmune hepatitis. World J Gastroenterol 2009; 15(5):578-582.
Bader TR, Beavers KL, Semelka RC. MR imaging features of primary sclerosing cholangitis: patterns of cirrhosis in relationship to clinical severity of disease. Radiology 2003; 226: 675-685.
Blachar A, Federle MP, Brancatelli G. Primary biliary cirrhosis: clinical, pathological, and helical CT findings in 53 patients. Radiology 2001; 220:329–336.
Valeasn S, Acalovschi M, Dumitrascu DL, et al. Hepatocellular carcinoma in patients with autoimmune hepatitis-a systematic review of the literature published between 1989-2016. Med Pharm Rep 2019; 92(2):99-105.
Hunter M, Loughrey MB, Gray M, et al. Evaluating distinctive features for early diagnosis of primary sclerosing cholangitis overlap syndrome in adults with autoimmune hepatitis. Ulster Med J 2011; 80(1):15-18.
DOI: http://dx.doi.org/10.36162/hjr.v7i2.468
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